28 Jul Lens Changes Associated With Radiation in the Cardiac Catheterization Laboratory
Here we take a look at TCT-198 Final Results of the IC-CATARACT (CATaracts Attributed to Radiation in the CaTh Lab) Study: Lens Changes Associated With Radiation in the Cardiac Catheterization Laboratory.
See the article here.
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Radiation exposure can cause lens opacities. We examined the relationship between occupational exposure to ionizing radiation and the prevalence of lens changes in interventional cardiologists (ICs) and catheterization laboratory (“cath-lab”) staff.
A cross-sectional study at an interventional cardiology conference was conducted for 3 consecutive years (2016 to 2018). Study participants were asked to complete a questionnaire, collecting data pertaining to occupational exposure to radiation and potential confounders for the development of cataracts, followed by slit-lamp examination and grading of lens findings.
A total of 188 individuals participated: 88% had occupational radiation exposure (age 49.5 ± 12 years; 81% men) and 12% were control subjects (age 37.6 ± 11 years; 64% men). In the exposed group, mean cumulative radiation dose to the lens was 4.79 Gy. The exposed participants group had a higher prevalence of Merriam-Focht (MF) ≥0.5 grade cortical and posterior subcapsular lens changes as compared with control subjects (58% vs. 27%; p = 0.006). The following factors were independently associated with lens changes: occupational radiation exposure (odds ratio [OR]: 5.11 [95% confidence interval (CI): 1.36 to 25.90]; p = 0.014); age (OR: 3.60 [95% CI: 1.60 to 8.53 for age 40 to 60 years]; p = 0.001; and OR: 21.50 [95% CI: 6.44 to 6.07]; p < 0.0001 for age >60 years), and female sex (OR: 3.47 [95% CI: 1.41 to 9.15]; p = 0.006). There was no difference between the prevalence of frank opacities in the 2 groups (24% vs. 9%; p = 0.094) (Figures A and B).
ICs and cath-lab staff had a higher prevalence of lens changes compared with unexposed control subjects, highlighting the importance of minimizing staff radiation exposure.